X0000116770588200912171132
| Read Date | 2009-12-17 11:32:00 |
|---|---|
| Read Number | X0000116770588200912171132 |
| Week | <nil> |
| Verified Crystal | |
| 3-Way Classifier | |
| 10-Way Classifier | |
| Cocktail | 10_C0999 |
| Screen | HWI Generation 10 |
| Name | pH | Concentration | SMILES |
|---|---|---|---|
| MES monohydrate | 6.8 | 0.1 M | O=S(=O)(O)CCN1CCOCC1 |
| HEPES-Na | 6.8 | 0.0 M | OCCN1CCN(CC1)CCS(=O)(=O)O… |
| HEPES-Na | 6.8 | 0.1 M | OCCN1CCN(CC1)CCS(=O)(=O)O… |
| PEG 3350 | 6.8 | 25.0 % (w/v) | C(CO)OC(CO)OC(CO)OC(CO)OC… |
| PIPES | 6.8 | 0.1 M | O=S(=O)(O)CCN1CCN(CCS(=O)… |
| Hexamminecobalt(III) Chloride | 6.8 | 0.3 % (w/v) | [Cl-].[Cl-].[Cl-].[Co+3].… |
 | HR4767C |
|---|---|
| Spine Status | crystal hits |
| Length | 200 aa |
| Mass | 23.57 kD |
| ext | 8940 |
| pI | 6.44 |
| Name | RecName: Full=Rho guanine nucleotide exchange factor 12;AltName: Full=Leukemia-associated RhoGEF; |
| Database References | NCBI UniProt |
| PFAM | PF09128 |
| PDB Structures | 1IAP (Best Match) |
| Gene | |
|---|---|
| Organism | Homo sapiens |
| Genus | Homo |
| Species | sapiens |
| Strain | |
| Sequence | INGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMKHLGVKVKEPRN |