X0000116770392200912171135
| Read Date | 2009-12-17 11:35:00 |
|---|---|
| Read Number | X0000116770392200912171135 |
| Week | <nil> |
| Verified Crystal | |
| 3-Way Classifier | |
| 10-Way Classifier | |
| Cocktail | 10_C0986 |
| Screen | HWI Generation 10 |
| Name | pH | Concentration | SMILES |
|---|---|---|---|
| HEPES-Na | 6.8 | 0.0 M | OCCN1CCN(CC1)CCS(=O)(=O)O… |
| HEPES-Na | 6.8 | 0.1 M | OCCN1CCN(CC1)CCS(=O)(=O)O… |
| PEG 3350 | 6.8 | 25.0 % (w/v) | C(CO)OC(CO)OC(CO)OC(CO)OC… |
| Dithioerythritol | 6.8 | 0.3 % (w/v) | SCC(O)C(O)CS |
| Caffeine | 6.8 | 0.3 % (w/v) | CN1C=NC2=C1C(=O)N(C(=O)N2… |
| L-Methionine | 6.8 | 0.3 % (w/v) | O=C(O)[C@@H](N)CCSC |
 | HR4767C |
|---|---|
| Spine Status | crystal hits |
| Length | 200 aa |
| Mass | 23.57 kD |
| ext | 8940 |
| pI | 6.44 |
| Name | RecName: Full=Rho guanine nucleotide exchange factor 12;AltName: Full=Leukemia-associated RhoGEF; |
| Database References | NCBI UniProt |
| PFAM | PF09128 |
| PDB Structures | 1IAP (Best Match) |
| Gene | |
|---|---|
| Organism | Homo sapiens |
| Genus | Homo |
| Species | sapiens |
| Strain | |
| Sequence | INGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMKHLGVKVKEPRN |