X0000116770036200912171140
| Read Date | 2009-12-17 11:40:00 |
|---|---|
| Read Number | X0000116770036200912171140 |
| Week | <nil> |
| Verified Crystal | |
| 3-Way Classifier | |
| 10-Way Classifier | |
| Cocktail | 10_C0969 |
| Screen | HWI Generation 10 |
| Name | pH | Concentration | SMILES |
|---|---|---|---|
| HEPES-Na | 6.8 | 0.0 M | OCCN1CCN(CC1)CCS(=O)(=O)O… |
| HEPES-Na | 6.8 | 0.1 M | OCCN1CCN(CC1)CCS(=O)(=O)O… |
| PEG 3350 | 6.8 | 25.0 % (w/v) | C(CO)OC(CO)OC(CO)OC(CO)OC… |
| L-Histidine | 6.8 | 0.2 % (w/v) | C1=C(N=CN1)C[C@@H](C(=O)O… |
| L-Isoleucine | 6.8 | 0.2 % (w/v) | CC[C@H](C)[C@@H](C(=O)O)N |
| L-Leucine | 6.8 | 0.2 % (w/v) | CC(C)C[C@@H](C(=O)O)N |
| L-Phenylalanine | 6.8 | 0.2 % (w/v) | c1ccc(cc1)C[C@@H](C(=O)O)… |
| L-Tryptophan | 6.8 | 0.2 % (w/v) | c1ccc2c(c1)c(c[nH]2)C[C@@… |
| L-Tyrosine | 6.8 | 0.2 % (w/v) | c1cc(ccc1C[C@@H](C(=O)O)N… |
 | HR4767C |
|---|---|
| Spine Status | crystal hits |
| Length | 200 aa |
| Mass | 23.57 kD |
| ext | 8940 |
| pI | 6.44 |
| Name | RecName: Full=Rho guanine nucleotide exchange factor 12;AltName: Full=Leukemia-associated RhoGEF; |
| Database References | NCBI UniProt |
| PFAM | PF09128 |
| PDB Structures | 1IAP (Best Match) |
| Gene | |
|---|---|
| Organism | Homo sapiens |
| Genus | Homo |
| Species | sapiens |
| Strain | |
| Sequence | INGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMKHLGVKVKEPRN |